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Direct Synthesis of Dialkylphosphites from White Phosphorus

Ziman Cai, Xiangzhe Zeng, Yumeng Zhang, Yan Liu, Guo Tang, Yufen Zhao

2022Advanced Synthesis & Catalysis15 citationsDOIOpen Access PDF

Abstract

Abstract Dialkyl phosphites (DAPIs), traditionally prepared from hazardous and corrosive PCl 3 , are the fundamental reactive starting materials used in organophosphorus chemistry. Here, a KBr‐mediated synthesis of DAPIs involving P 4 , alcohols and water is presented. With the use of silica gel as the catalyst, oxone as the safe oxidant, industrially important (EtO) 2 P(O)H, (i‐PrO) 2 P(O)H and (MeO) 2 P(O)H are prepared in 70–90% yields. Furthermore, rare metal extractant bis(2‐ethylhexyl) phosphate (D2EHPA) is obtained in 73% yield. The reaction is characterized by a complete conversion of white phosphorus. Moreover, this method can be easily adapted to large‐scale preparation. magnified image

Topics & Concepts

ChemistryWhite PhosphorusCatalysisYield (engineering)PhosphorusPhosphateNuclear chemistryOrganic chemistryInorganic chemistryMetallurgyMaterials scienceOrganophosphorus compounds synthesisPhosphorus compounds and reactionsSynthesis and Reactivity of Sulfur-Containing Compounds
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