A phenoxy-bridged trinuclear Ni(<scp>ii</scp>) complex: synthesis, structural elucidation and molecular docking with viral proteins
Sunil Kumar, Mukesh Choudhary
Abstract
A novel phenoxy-bridged trinuclear nickel( ii ) complex [Ni 3 (μ-L) 2 (bipy) 3 ](1) (where H 3 L= ( E )-2-hydroxy- N -(2-hydroxy-3,5-diiodophenyl)-3,5-diiodobenzohydrazonic acid, bipy = 2,2′-bipyridyl) has been designed and synthesized as a potential antivirus drug candidate.
Topics & Concepts
ChemistryStereochemistryDocking (animal)NickelOrganic chemistryMedicineNursingMetal complexes synthesis and propertiesHIV/AIDS drug development and treatmentRNA and protein synthesis mechanisms