Anicteric Leptospirosis-Associated Meningitis in a Tropical Urban Environment, Brazil
Scott A. Nabity, Guilherme Araújo, José E. Hagan, Alcinéia O. Damião, Mitermayer Galvão dos Reis, Albert I. Ko, Guilherme S. Ribeiro
Abstract
T he clinical signs of leptospirosis can vary widely, which complicates timely diagnosis and targeted therapy. Aseptic meningitis associated with Leptospira infection, hereafter termed leptospirosis-associated meningitis (LAM), has been well described (1-3). However, clinicians diagnose atypical forms of leptospirosis less frequently, particularly in the absence of classic signs (i.e., renal insufficiency or hepatitis). Detection requires a high level of clinical suspicion, and even then imperfect diagnostics for leptospirosis limit timely confirmation.
Topics & Concepts
Aseptic meningitisLeptospirosisMeningitisMedicineCerebrospinal fluidPediatricsVirologyInternal medicineLeptospirosis research and findings