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The Evolution of DNA Extraction Methods

Preetha J. Shetty

2020American Journal of Biomedical Science & Research133 citationsDOIOpen Access PDF

Abstract

Since the first DNA extraction performed by Friedrich Miescher in 1869, scientists have made extraordinary progress in designing extraction methods that are more reliable, easier and faster to perform, more cost-effective and produce a higher yield. The classic liquid-liquid DNA extraction method involves the use of organic and inorganic reagents such as phenol-chloroform which pose a toxic threat to humans.

Topics & Concepts

Extraction (chemistry)DNA extractionYield (engineering)DNAChloroformReagentPhenolChromatographyChemistryBiochemical engineeringComputational biologyBiologyMaterials scienceOrganic chemistryEngineeringBiochemistryPolymerase chain reactionMetallurgyGeneCRISPR and Genetic EngineeringRace, Genetics, and Society
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