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A case of SARS-CoV-2 pneumonia with successful antiviral therapy in a 77-year-old man with a heart transplant

Daniel Mathies, Dominic Rauschning, Ulrike Wagner, Frank Mueller, Maja Maibaum, Christin Binnemann, Stephan Waldeck, Katrin Thinnes, Michael Braun, Willi Schmidbauer, Ralf Matthias Hagen, Christoph Bickel

2020American Journal of Transplantation35 citationsDOIOpen Access PDF

Abstract

The SARS-CoV-2 infection can be seen as a single disease, but it also affects patients with relevant comorbidities who may have an increased risk of a severe course of infection. In this report, we present a 77-year-old patient with a heart transplant receiving relevant immunosuppressive therapy who tested positive for SARS-CoV-2 after several days of dyspnea, dry cough, and light general symptoms. Computed tomography confirmed interstitial pneumonia. The patient received antiviral therapy with hydroxychloroquine and showed no further deterioration of the clinical state. After 12 days of hospitalization, the patient was released; he was SARS-CoV-2 negative and completely asymptomatic. The SARS-CoV-2 infection can be seen as a single disease, but it also affects patients with relevant comorbidities who may have an increased risk of a severe course of infection. In this report, we present a 77-year-old patient with a heart transplant receiving relevant immunosuppressive therapy who tested positive for SARS-CoV-2 after several days of dyspnea, dry cough, and light general symptoms. Computed tomography confirmed interstitial pneumonia. The patient received antiviral therapy with hydroxychloroquine and showed no further deterioration of the clinical state. After 12 days of hospitalization, the patient was released; he was SARS-CoV-2 negative and completely asymptomatic.

Topics & Concepts

MedicinePneumoniaSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)Antiviral therapyIntensive care medicineHeart transplantation2019-20 coronavirus outbreakBetacoronavirusVirologyViral pneumoniaImmunologyTransplantationInternal medicineInfectious disease (medical specialty)VirusOutbreakDiseaseChronic hepatitisCOVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 ResearchLong-Term Effects of COVID-19