Preventive effect of dioscin against monosodium urate-mediated gouty arthritis through inhibiting inflammasome NLRP3 and TLR4/NF-κB signaling pathway activation: an in vivo and in vitro study
Jieru Han, Guangyu Shi, Wenhao Li, Ying Xie, Fuzhen Li, Deyou Jiang
Topics & Concepts
InflammasomeChemistryIn vivoPharmacologyNF-κBTLR4InflammationCaspase 1ArthritisIκBαSignal transductionBiochemistryImmunologyMedicineReceptorBiologyBiotechnologyInflammasome and immune disordersGout, Hyperuricemia, Uric AcidCancer-related molecular mechanisms research