Global, regional, and national burden of Burkitt lymphoma from 1990 to 2021 and predictions to 2030: a systematic analysis for the Global Burden of Disease Study 2021
Ying Wang, Ziyuan Shen, Chenlu He, Xing Xing, Zaixiang Tan, Wei Sang
Abstract
Burkitt lymphoma (BL) is a highly aggressive form of non-Hodgkin lymphoma that predominantly affects young males. The age-standardized incidence rates (ASIRs) of BL show significant variation, with disparities ranging from three- to five-fold across different continents [ 1 ]. This variation is most pronounced in equatorial Africa, where the incidence rates exceed 4 cases per million person-years between 10°N to 10°S latitude, making BL endemic to this region [ 2 , 3 ]. Survival outcomes for BL are influenced by multiple factors, including disease stage, geographic location, ethnicity, and treatment approaches [ 4 , 5 ].
Topics & Concepts
Burden of diseaseDisease burdenMedicineLymphomaBurkitt's lymphomaDiseaseMEDLINEImmunologyIntensive care medicinePolitical scienceInternal medicineLawLymphoma Diagnosis and TreatmentMultiple and Secondary Primary CancersOvarian cancer diagnosis and treatment