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Graph deep learning for the characterization of tumour microenvironments from spatial protein profiles in tissue specimens

Zhenqin Wu, Alexandro E. Trevino, Eric Q. Wu, Kyle Swanson, Honesty J. Kim, H. Blaize D’Angio, Ryan Preska, Gregory W. Charville, Piero Dalerba, Ann Marie Egloff, Ravindra Uppaluri, Umamaheswar Duvvuri, Aaron T. Mayer, James Zou

2022Nature Biomedical Engineering151 citationsDOI

Topics & Concepts

Computational biologyDeep learningTranscriptomeImmunofluorescenceTumour heterogeneityBiologyComputer sciencePathologyArtificial intelligenceCancerMedicineGene expressionGeneImmunologyAntibodyGeneticsSingle-cell and spatial transcriptomicsBioinformatics and Genomic NetworksCell Image Analysis Techniques
Graph deep learning for the characterization of tumour microenvironments from spatial protein profiles in tissue specimens | Litcius