Discovery of ( ±)-3-(1H-pyrazol-1-yl)-6,7-dihydro-5H-[1,2,4]triazolo[3,4-b][1,3,4] thiadiazine derivatives with promising in vitro anticoronavirus and antitumoral activity
Parameshwara Chary Jilloju, Leentje Persoons, Sathish Kumar Kurapati, Dominique Schols, Steven De Jonghe, Dirk Daelemans, Rajeswar Rao Vedula
Topics & Concepts
ChemistryMoietyPhenacylIn vitroStereochemistryAcetoneBiological activityTriazoleThiolCombinatorial chemistryMedicinal chemistryBiochemistryOrganic chemistrySynthesis and biological activitySynthesis and Characterization of Heterocyclic CompoundsQuinazolinone synthesis and applications