The self-assembly of a hybrid photosensitizer for the synergistically enhanced photodynamic/photothermal therapy
Jia Chen, Yunxiao Cui, Kewei Song, Tianqi Liu, Luyao Zhou, Biqing Bao, Ruibing Wang, Lianhui Wang
Abstract
= 0.175). The in vitro and in vivo experiments showed that BBPP possessed negligible dark cytotoxicity and a better phototherapeutic outcome than BBP. The proof-of-concept of the POSS hybrid photosensitizer offers guidance for the construction of single-component and PDT/PTT-balanced NIR nanoagents to promote the cancer therapeutic efficacy in the future.
Topics & Concepts
PhotosensitizerPhotodynamic therapyPhotothermal therapyBODIPYChemistryPhotochemistryNanotechnologyFluorescenceMaterials scienceOpticsOrganic chemistryPhysicsNanoplatforms for cancer theranosticsLuminescence and Fluorescent MaterialsPhotodynamic Therapy Research Studies