Sensing of ATP via the Purinergic Receptor P2RX7 Promotes CD8+ Trm Cell Generation by Enhancing Their Sensitivity to the Cytokine TGF-β
Henrique Borges da Silva, Changwei Peng, Haiguang Wang, Kelsey M. Wanhainen, Chaoyu Ma, Sharon Lopez, Alexander Khoruts, Nu Zhang, Stephen C. Jameson
Topics & Concepts
Purinergic receptorBiologyCD8Cell biologyPurinergic signallingT cellReceptorJurkat cellsCytokineCytotoxic T cellCellExtracellularImmune systemImmunologyAdenosine receptorBiochemistryAgonistIn vitroAdenosine and Purinergic SignalingImmune Cell Function and InteractionImmune cells in cancer