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Rewiring cancer drivers to activate apoptosis

Sai Gourisankar, A. Krokhotin, Wenzhi Ji, Xiaofan Liu, Chiung-Ying Chang, Samuel H. Kim, Zhengnian Li, Wendy Wenderski, Juste Simanauskaite, Haopeng Yang, Hannes Vogel, Tinghu Zhang, Michael R. Green, Nathanael S. Gray, Gerald R. Crabtree

2023Nature162 citationsDOIOpen Access PDF

Topics & Concepts

Transcription factorProgrammed cell deathBiologyPromoterCancer cellEnhancerBCL6EpigeneticsCell biologyCancer researchGeneApoptosisMolecular biologyGene expressionGeneticsCancerB cellGerminal centerAntibodyProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysCancer Mechanisms and Therapy
Rewiring cancer drivers to activate apoptosis | Litcius