Hydrogen movements in the oxidative half-reaction of kynurenine 3-monooxygenase from Pseudomonas fluorescens reveal the mechanism of hydroxylation
Brett A. Beaupre, Karen R. Reabe, Joseph Roman, Graham R. Moran
Topics & Concepts
HydroxylationChemistryKinetic isotope effectSubstrate (aquarium)StereochemistryReaction rate constantMedicinal chemistryOxidative phosphorylationDeuteriumPhotochemistryOrganic chemistryBiochemistryKineticsEnzymeBiologyQuantum mechanicsPhysicsEcologyTryptophan and brain disordersMental Health Research TopicsGut microbiota and health