γ-Glutamyltranspeptidase and pH based “AND” logic gate fluorescent probe for orthotopic breast tumor imaging
Lina Zhang, Hong Zhang, Shan‐Yong Chen, Yan-Zhao Liu, Xiaohua Yang, Fei‐Fan Xiang, Yanhong Liu, Kun Li, Xiao‐Qi Yu
Abstract
-amine Si-Rhodamine, which combined γ-glutamyl transpeptidase and pH dual-responsive sites. The features of Si-NH2-Glu enable it to be applied in orthotopic tumor imaging and fluorescence-guided surgery.
Topics & Concepts
FluorescenceChemistryCancer researchMedicinePhysicsOpticsNanoplatforms for cancer theranosticsSulfur Compounds in BiologyCancer, Hypoxia, and Metabolism