In vitro evaluation of the effect of mutations in primer binding sites on detection of SARS-CoV-2 by RT-qPCR
Fee Zimmermann, Maria Letizia Urban, Christian Krüger, Mathias C. Walter, Roman Wölfel, Katrin Zwirglmaier
Topics & Concepts
BiologyPrimer (cosmetics)VirologyMolecular biologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)In vitroReal-time polymerase chain reactionMutationGeneticsCoronavirus disease 2019 (COVID-19)GeneDiseaseMedicineInfectious disease (medical specialty)PathologyOrganic chemistryChemistrySARS-CoV-2 and COVID-19 ResearchSARS-CoV-2 detection and testingAdvanced biosensing and bioanalysis techniques