Ajugol enhances TFEB-mediated lysosome biogenesis and lipophagy to alleviate non-alcoholic fatty liver disease
Heng Zhang, Jun Lu, Hao Liu, Lingling Guan, Shiqing Xu, Zai Wang, Yang Qiu, Honglin Liu, Liang Peng, Xiuli Men
Topics & Concepts
TFEBAutophagySteatosisLysosomeAutophagosomeCell biologyLipid dropletFatty liverSteatohepatitisBiogenesisMechanistic target of rapamycinChemistryBiologyCancer researchBiochemistryEndocrinologyInternal medicineMedicineDiseaseGeneApoptosisEnzymeAutophagy in Disease and TherapyLipid metabolism and biosynthesisSphingolipid Metabolism and Signaling