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Palladium Supported on Silk Fibroin for Suzuki–Miyaura Cross‐Coupling Reactions

Giorgio Rizzo, Gianluigi Albano, Marco Lo Presti, Antonella Milella, Fiorenzo G. Omenetto, Gianluca M. Farinola

2020European Journal of Organic Chemistry32 citationsDOI

Abstract

Silk fibroin supported Pd (Pd/SF) has been prepared and used as catalyst in Suzuki–Miyaura cross‐coupling reactions in water/ethanol (4:1 v/v) mixture. The reactions proceed rapidly with aryl iodides and boronic acids with different electronic properties using low metal loading (0.38 mol‐%). Pd/SF exhibits better recyclability compared to other biopolymer‐supported Pd catalysts, up to nineteen cycles without loss of activity.

Topics & Concepts

FibroinChemistryPalladiumCatalysisCoupling reactionArylBiopolymerPolymer chemistrySuzuki reactionOrganic chemistryChemical engineeringSILKComposite materialPolymerMaterials scienceAlkylEngineeringSilk-based biomaterials and applicationsCatalytic Cross-Coupling ReactionsChemical Synthesis and Analysis
Palladium Supported on Silk Fibroin for Suzuki–Miyaura Cross‐Coupling Reactions | Litcius