Dramatic response to PARP inhibition in a PALB2-mutated breast cancer: moving beyond BRCA
T. Grellety, Florent Peyraud, Nicolas Sévenet, Olivier Trédan, Nadine Dohollou, Emmanuelle Barouk-Simonet, Michèle Kind, Michel Longy, Jean‐Yves Blay, Antoine Italiano
Topics & Concepts
MedicineBreast cancerOncologyOlaparibInternal medicineAnastrozolePARP inhibitorBRCA mutationTaxaneCancerTamoxifenGenePolymeraseBiochemistryPoly ADP ribose polymeraseChemistryPARP inhibition in cancer therapyBRCA gene mutations in cancerDNA Repair Mechanisms