Cobalt-catalyzed carbonylation of the C–H bond
Lukass Lukasevics, Liene Grigorjeva
Abstract
Direct carbonylation of the C-H bond is a great tool for installing a carbonyl group in a wide variety of substrates. This review summarizes the C-H bond carbonylation methodologies using the cobalt-catalyzed C-H bond functionalization approach. Despite the fact that cobalt-catalyzed carbonylation methodologies have been known since Murahashi's report in 1955, this area is still underdeveloped, particularly carbonylation of the C(sp3)-H bond.
Topics & Concepts
CarbonylationCatalysisCobaltChemistryCombinatorial chemistryOrganic chemistryCarbon monoxideCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling ReactionsSynthesis and Catalytic Reactions