Angioimmunoblastic T-cell lymphoma unmasked by treatment with dupilumab
Zi-Yi Choo, Adesola A. Akinyemi, Thomas L. Cibull, Stephanie Mehlis, Jason B. Waldinger
Abstract
Angioimmunoblastic T-cell lymphoma (AITL) is an aggressive peripheral T-cell lymphoma. Clinically, AITL presents in older individuals with B-symptoms, such as drenching night sweats or fever, and generalized lymphadenopathy.1 Skin rash occurs in close to 50% of cases.2 We report a case of AITL presenting as generalized pruritus with lymphadenopathy developing in the setting of dupilumab therapy.
Topics & Concepts
Angioimmunoblastic T-cell lymphomaMedicineRashLymphomaDupilumabDermatologyGeneralized lymphadenopathyT cellPathologyImmunologyImmune systemAtopic dermatitisLymphoma Diagnosis and TreatmentCutaneous lymphoproliferative disorders researchVascular Tumors and Angiosarcomas