Mild stimulatory effect of a probiotic mix on bone mass when treatment is initiated 1.5 weeks after ovariectomy in mice
Claes Ohlsson, Lina Lawenius, Annica Andersson, K. Gustafsson, Jianyao Wu, Marie K. Lagerquist, Sofia Movérare‐Skrtic, Ulrika Islander, Klara Sjögren
Abstract
The probiotic L. mix exerted a mild stimulatory effect on trabecular and cortical bone width when treatment is initiated 1.5 wk after ovariectomy in mice. This effect was associated with effects on bone-protecting regulatory T-cells. The results suggest that L. mix may exert beneficial effects on bone mass when treatment is started after ovariectomy.
Topics & Concepts
ProbioticBone massEndocrinologyInternal medicineMedicineChemistryBiologyOsteoporosisGeneticsBacteriaBone Metabolism and DiseasesDigestive system and related healthInflammatory Bowel Disease