Stroma-targeted nanoparticles that remodel stromal alignment to enhance drug delivery and improve the antitumor efficacy of Nab-paclitaxel in pancreatic ductal adenocarcinoma models
Dan Wei, Xiaoyu Cheng, Chong Du, Yazhou Wang, Jingyi Sun, Chen Li, Jing Wu, Xiaodong Tian, Ying Zhao, Guangjun Nie, Yinmo Yang
Topics & Concepts
Stromal cellStromaCancer researchPancreatic cancerExtracellular matrixDrug deliveryPaclitaxelTargeted drug deliveryLysyl oxidaseChemistryCancerMedicinePathologyImmunohistochemistryInternal medicineBiochemistryOrganic chemistryMicrobial metabolism and enzyme functionCancer, Hypoxia, and MetabolismCaveolin-1 and cellular processes