An optimally designed anti-human CD40 antibody with potent B cell suppression for the treatment of autoimmune diseases
Helen Wu, Kerry-Leigh Ralph, Eliud Sepuldeva, Gale Hansen, Hua Li, Zhong-Fu Huang, Dongmei Liu, Michael Dziegelewski, Jennifer Ahlberg, Lee Frego, Steve Fogal, Susan van Tongeren, Christine Grimaldi, Tobias Litzenberger, David H. Presky, Sanjaya Singh, Scott R. Brodeur, Rachel Kroe‐Barrett
Topics & Concepts
AntibodyCD40ImmunologyMedicineMonoclonal antibodyRheumatoid arthritisAutoimmunityB cellBiologyIn vitroCytotoxic T cellBiochemistryImmunotherapy and Immune ResponsesMonoclonal and Polyclonal Antibodies ResearchT-cell and B-cell Immunology