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Gut microbiome and liver diseases

Jun Xu, Ning Chen, Li Zhou, Yulan Liu

2024Fundamental Research13 citationsDOIOpen Access PDF

Abstract

Symbiotic microbiota plays a crucial role in the education, development, and maintenance of the host immune system, significantly contributing to overall health. Through the gut-liver axis, the gut microbiota and liver have a bidirectional relationship that is becoming increasingly evident as more research highlights the translocation of the gut microbiota and its metabolites. The focus of this narrative review is to examine and discuss the importance of the gut-liver axis and the enterohepatic barrier in maintaining overall health. Additionally, we emphasize the crucial role of the gut microbiome in liver diseases and explore potential therapeutic strategies for liver diseases by manipulating the microbiota.

Topics & Concepts

MicrobiomeGut microbiomeBiologyComputational biologyEvolutionary biologyBioinformaticsGut microbiota and healthDiet and metabolism studiesGastrointestinal motility and disorders
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