Role of Ca <sup>2+</sup> transients at the node of the mouse embryo in breaking of left-right symmetry
Katsutoshi Mizuno, Kei Shiozawa, Takanobu A. Katoh, Katsura Minegishi, Takahiro Ide, Yayoi Ikawa, Hiromi Nishimura, Katsuyoshi Takaoka, Takeshi Itabashi, Atsuko H. Iwane, Junichi Nakai, Hidetaka Shiratori, Hiroshi Hamada
Abstract
Left-right (L-R) asymmetric intraciliary calcium transient at the node is the determinant of L-R axis in mice.
Topics & Concepts
EmbryoBilateral symmetrySymmetry (geometry)Node (physics)PhysicsSymmetry breakingNODALBiologyAnatomyMathematicsCell biologyParticle physicsGeometryEngineeringAcousticsMechanical engineeringGenetic and Kidney Cyst DiseasesCongenital heart defects researchRenal and related cancers