Nanobubble-mediated co-delivery of Ce6 and miR-195 for synergized sonodynamic and checkpoint blockade combination therapy with elicitation of robust immune response in hepatocellular carcinoma
Yao Ma, Jinlin Li, Yun Zhao, Bing Hu, Yun Liu, Chaoqi Liu
Topics & Concepts
Cancer researchmicroRNASonodynamic therapyCytotoxic T cellImmunotherapyImmune systemImmune checkpointChemistryPD-L1CTL*ApoptosisImmunogenic cell deathMedicineCD8ImmunologyGeneIn vitroBiochemistryNanoplatforms for cancer theranosticsExtracellular vesicles in diseaseUltrasound and Hyperthermia Applications