Theranostic Phthalocyanine and Naphthalocyanine Nanoparticles for Photoacoustic Imaging and Photothermal Therapy of Tumors
Yiran Tian, Nicole Carrillo-Malani, Kailin Feng, Joann M. Miller, Theresa M. Busch, Karthik M. Sundaram, Zhiliang Cheng, Ahmad Amirshaghaghi, Andrew Tsourkas
Abstract
CuNC(Octa)-loaded micelles represent a promising theranostic agent for PA imaging and PTT. The ability to utilize conventional ultrasound in combination with PA imaging enables the simultaneous acquisition of information about tumor morphology and micelle accumulation. PTT with CuNC(Octa)-loaded micelles can lead to the complete eradication of highly invasive tumors.
Topics & Concepts
MicellePhotothermal therapyPhotoacoustic imaging in biomedicineAbsorbanceMaterials scienceNanorodNanoshellNanoparticleIn vivoPhthalocyanineChemistryNanotechnologyOrganic chemistryChromatographyAqueous solutionBiologyPhysicsBiotechnologyOpticsNanoplatforms for cancer theranosticsPhotoacoustic and Ultrasonic ImagingPhotodynamic Therapy Research Studies