<i>In Vitro</i> Susceptibility of <i>Achromobacter</i> Species Isolated from Cystic Fibrosis Patients: a 6-Year Survey
Margo Olbrecht, Fedoua Echahidi, Denis Piérard, Charlotte Peeters, Peter Vandamme, Ingrid Wybo, Thomas Demuyser
Abstract
isolates for 16 antibiotics from 2017 to 2022. The highest susceptibility was found for piperacillin-tazobactam (70%) and ceftazidime-avibactam (62%). Between 30% and 49% of strains were susceptible to tigecycline, ceftazidime, and meropenem. We applied species-specific Achromobacter xylosoxidans breakpoints for piperacillin-tazobactam, meropenem, and trimethoprim-sulfamethoxazole and EUCAST pharmacokinetic/pharmacodynamic (PK/PD) breakpoints for the others. A. xylosoxidans was the most frequently isolated species, followed by Achromobacter insuavis and Achromobacter ruhlandii.
Topics & Concepts
Cystic fibrosisAchromobacterIn vitroMicrobiologyMedicineBiologyInternal medicineGeneticsBacteriaPseudomonasInfections and bacterial resistancePlant Pathogenic Bacteria StudiesAntibiotic Resistance in Bacteria