A cascade Fermat spiral microfluidic mixer chip for accurate detection and logic discrimination of cancer cells
Shiyu Zeng, Xiaocheng Sun, Xinhua Wan, Changcheng Qian, Wenkai Yue, A. S. M. Muhtasim Fuad Sohan, Xiaodong Lin, Binfeng Yin
Abstract
cells per mL with a limit of detection (LOD) as low as 17 cells per mL. Interestingly, the cascaded AND logic gate is integrated with CFSMMC for the first time to distinguish cancer cells from normal cells under the control of logic functions, which exhibits great potential in the development of one-step rapid and intelligent detection and logic discrimination.
Topics & Concepts
Cancer cellDetection limitNanotechnologyBiosensorFluorescenceMaterials scienceMicrofluidicsChemistryCancerBiophysicsOptoelectronicsBiologyChromatographyOpticsPhysicsGeneticsAdvanced biosensing and bioanalysis techniquesBiosensors and Analytical DetectionMicrofluidic and Capillary Electrophoresis Applications