Targeted degradation of NDUFS1 by agrimol B promotes mitochondrial ROS accumulation and cytotoxic autophagy arrest in hepatocellular carcinoma
Lixia Dong, Li Luo, Zihao Wang, Shan Lian, Mao Wang, Xingyun Wu, Jiawu Fan, Yan Zeng, Sijia Li, Sinan Lv, Yurong Yang, Rong Chen, Enhao Shen, Wenyong Yang, Changlong Li, Kui Wang, Enhao Shen, Wenyong Yang, Changlong Li, Kui Wang
Topics & Concepts
AutophagySorafenibChemistryCytotoxic T cellAutophagosomeCancer researchApoptosisProgrammed cell deathCell biologyHepatocellular carcinomaIn vitroBiologyBiochemistryAutophagy in Disease and TherapySirtuins and Resveratrol in MedicineGenomics, phytochemicals, and oxidative stress