Engineered regulatory T cells expressing myelin-specific chimeric antigen receptors suppress EAE progression
Alessandra de Paula Pohl, Anja Schmidt, Ai-Hong Zhang, Tania D. Maldonado, Christoph Königs, David W. Scott
Topics & Concepts
Myelin oligodendrocyte glycoproteinChimeric antigen receptorExperimental autoimmune encephalomyelitisFOXP3Myelin basic proteinImmunologyBiologyT-cell receptorMyelinAntigenMultiple sclerosisCancer researchT cellImmune systemNeuroscienceCentral nervous systemCAR-T cell therapy researchT-cell and B-cell ImmunologyImmune Cell Function and Interaction