Impact of sinus surgery on type 2 airway and systemic inflammation in asthma
Kazuki Hamada, Keiji Oishi, Ayumi Chikumoto, Keita Murakawa, Yuichi Ohteru, Kazuki Matsuda, Sho Uehara, Ryo Suetake, Shuichiro Ohata, Yoriyuki Murata, Yoshikazu Yamaji, Maki Asami‐Noyama, Kosuke Ito, Nobutaka Edakuni, Tsunahiko Hirano, Kazuto Matsunaga
Abstract
In eosinophilic CRSwNP patients with asthma, sinus surgery impacts asthma control through the suppression of airway/systemic type 2 inflammation. The present study reinforced the common pathophysiology of type 2 inflammation between the upper and lower airways.
Topics & Concepts
MedicineAsthmaExhaled nitric oxideEosinophilEosinophilicGastroenterologyAirwayInternal medicineSystemic inflammationInflammationAnesthesiaImmunologySpirometryPathologyAsthma and respiratory diseasesSinusitis and nasal conditionsAllergic Rhinitis and Sensitization