Pharmacological PDGFRβ inhibitors imatinib and sunitinib cause human brain pericyte death in vitro
Natalie E. King, Jo‐Maree Courtney, Lachlan S. Brown, Catherine G. Foster, Jake M. Cashion, Emily Attrill, Dino Premilovac, David W. Howells, Brad A. Sutherland
Topics & Concepts
PericyteSunitinibPlatelet-derived growth factor receptorImatinibCancer researchTyrosine kinaseAngiogenesisTyrosine-kinase inhibitorReceptor tyrosine kinaseBiologyCancerPhosphorylationPharmacologyMedicineReceptorSignal transductionCell biologyInternal medicineGrowth factorIn vitroEndothelial stem cellBiochemistryMyeloid leukemiaFibroblast Growth Factor ResearchKruppel-like factors researchBarrier Structure and Function Studies