A versatile CRISPR-Cas13d platform for multiplexed transcriptomic regulation and metabolic engineering in primary human T cells
Victor Tieu, Elena Sotillo, Jeremy Bjelajac, Xingyu Chen, Meena Malipatlolla, Justin A. Guerrero, Peng Xu, Patrick J. Quinn, Chris Fisher, Dorota D. Klysz, Crystal L. Mackall, Lei S. Qi
Topics & Concepts
BiologyCRISPRTranscriptomeComputational biologyPrimary (astronomy)Genome editingGenome engineeringGeneticsCell biologyGeneGene expressionPhysicsAstronomyCAR-T cell therapy researchCRISPR and Genetic EngineeringViral Infectious Diseases and Gene Expression in Insects