Synthesis and biological evaluation of novel pyrazolo[3,4-b]pyridines as cis-restricted combretastatin A-4 analogues
Xie‐Er Jian, Fang Yang, Cui-Shan Jiang, Wen‐Wei You, Pei‐Liang Zhao
Topics & Concepts
HeLaChemistryTubulinStereochemistryCombretastatinPyridineColchicineDerivative (finance)Cell growthBiological activityCell cultureMicrotubuleIn vitroBiochemistryMedicinal chemistryCell biologyEconomicsInternal medicineMedicineGeneticsFinancial economicsBiologySynthesis and biological activityCancer therapeutics and mechanismsClick Chemistry and Applications