SHP2 clinical phenotype, cancer, or RASopathies, can be predicted by mutant conformational propensities
Yonglan Liu, Wengang Zhang, Hyunbum Jang, Ruth Nussinov
Topics & Concepts
Noonan syndromeMutationCancerPhenotypeGeneticsPTPN11MutantBiologyCancer researchCostello syndromeGeneKRASProtein Tyrosine PhosphatasesATP Synthase and ATPases ResearchGalectins and Cancer Biology