An Improved Method for Cytochrome P450 Reaction Phenotyping Using a Sequential Qualitative-Then-Quantitative Approach
Angela C. Doran, Alyssa Dantonio, Gabrielle M. Gualtieri, Amanda Balesano, Connor Landers, Woodrow Burchett, Theunis C. Goosen, R. Scott Obach
Topics & Concepts
PharmacologyCYP2C19CYP2D6Cytochrome P450CYP2C9ChemistryPharmacokineticsEnzymeBiochemistryMedicinePharmacogenetics and Drug MetabolismComputational Drug Discovery MethodsMetabolomics and Mass Spectrometry Studies