Loss of TDP-43 splicing repression occurs early in the aging population and is associated with Alzheimer’s disease neuropathologic changes and cognitive decline
Koping Chang, Jonathan P. Ling, Javier Redding‐Ochoa, Yang An, Ling Li, Stephanie Dean, Thomas G. Blanchard, Tatiana Pylyukh, Alexander Barrett, Katherine E. Irwin, Abhay Moghekar, Susan M. Resnick, Philip C. Wong, Juan C. Troncoso
Topics & Concepts
Verbal fluency testPsychologyCognitive declineAlzheimer's diseaseBoston Naming TestDementiaPopulationCognitionNeurosciencePathologyMedicineDiseaseNeuropsychologyEnvironmental healthAlzheimer's disease research and treatmentsAmyotrophic Lateral Sclerosis ResearchRNA Research and Splicing