Synthesis of isoxazolidines <i>via</i> catalyst-free one-pot three-component cycloaddition of sulfoxonium ylides, nitrosoarenes and alkenes
Xing Li, Pingan Zhai, Yongsheng Fang, Wenhui Li, Honghong Chang, Wen‐Chao Gao
Abstract
A general and practical strategy for the construction of various keto-substituted isoxazolidines <italic>via</italic> one-pot three-component reaction of easily accessible, safer and more stable sulfoxonium ylides, nitrosoarenes and olefins is described.
Topics & Concepts
ChemistryCycloadditionComponent (thermodynamics)CatalysisSAFERCombinatorial chemistryOrganic chemistryComputer sciencePhysicsThermodynamicsComputer securitySynthesis and Catalytic ReactionsCyclopropane Reaction MechanismsSulfur-Based Synthesis Techniques