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The Giese reaction of alkyl bromides using amine carboxyboranes

Changhee Park, Seyun Gi, Seongkyeong Yoon, Seong Jung Kwon, Sunggi Lee

2025Organic Chemistry Frontiers12 citationsDOI

Abstract

The Giese reaction of alkyl bromides was achieved using amine carboxyboranes as ligated boryl radical precursors. Furthermore, ligated boryl radicals were utilized to establish carbon–boron bonds.

Topics & Concepts

ChemistryAlkylAmine gas treatingHalogenMedicinal chemistryCombinatorial chemistryPolymer chemistryOrganic chemistryPlant-based Medicinal ResearchAsymmetric Synthesis and CatalysisChemical Reactions and Isotopes