Suppression of adenosine-to-inosine (A-to-I) RNA editome by death associated protein 3 (DAP3) promotes cancer progression
Jian Han, Ömer An, HuiQi Hong, Tim Hon Man Chan, Yangyang Song, Haoqing Shen, Sze Jing Tang, Jaymie Siqi Lin, Vanessa Hui En Ng, Daryl Jin Tai Tay, Fernando Bellido Molías, Priyankaa Pitcheshwar, Hui Tan, Henry Yang, Leilei Chen
Abstract
, is accumulated in tumors. In sum, cancer cells may acquire malignant properties for their survival advantage through suppressing RNA editome by DAP3.
Topics & Concepts
InosineAdenosineCancerRNACancer researchMedicineBiologyComputational biologyInternal medicineGeneticsGeneRNA regulation and diseaseCRISPR and Genetic EngineeringRNA Research and Splicing