A highly active Cp*Ir complex with an anionic N,N-donor chelate ligand catalyzes the robust regeneration of NADH under physiological conditions
Lijun Zhao, Zequn Yin, Yusheng Shi, Wen Sun, Libo Sun, Huijuan Su, Xun Sun, Weiling Zhang, Linyan Xia, Caixia Qi
Abstract
Anionic N,N-donor ligand chelate iridium complex [Cp*Ir(pba)Cl] 3 was developed, and exhibited the highest activity for NADH regeneration so far and stable chemoenzymatical coordinate catalytic performance for acetophenone enantioselective hydrogenation.
Topics & Concepts
AcetophenoneIridiumLigand (biochemistry)ChemistryEnantioselective synthesisChelationCatalysisRegeneration (biology)StereochemistryCombinatorial chemistryMedicinal chemistryOrganic chemistryReceptorBiochemistryBiologyCell biologyAsymmetric Hydrogenation and CatalysisNanomaterials for catalytic reactionsMetal-Organic Frameworks: Synthesis and Applications