Candida auris Cell Wall Mannosylation Contributes to Neutrophil Evasion through Pathways Divergent from Candida albicans and Candida glabrata
Mark V. Horton, Chad Johnson, Robert Żarnowski, Brody D. Andes, Taylor J. Schoen, John F. Kernien, Douglas W. Lowman, Michael Kruppa, Zuchao Ma, David L. Williams, Anna Huttenlocher, Jeniel E. Nett
Abstract
The emerging fungal pathogen Candida auris presents a global public health threat. Therapeutic options are often limited for this frequently drug-resistant pathogen, and mortality rates for invasive disease are high.
Topics & Concepts
Candida aurisFungal pathogenCandida albicansCandida glabrataPathogenMicrobiologyBiologyCandida infectionsFungal diseaseAntifungalAntifungal resistance and susceptibilityFungal Infections and StudiesNeutrophil, Myeloperoxidase and Oxidative Mechanisms