Litcius/Paper detail

Iron-Catalyzed α,β-Dehydrogenation of Carbonyl Compounds

Xiaowei Zhang, Guo-Qing Jiang, Shu‐Hui Lei, Xiang‐Huan Shan, Jian‐Ping Qu, Yan‐Biao Kang

2021Organic Letters49 citationsDOI

Abstract

An iron-catalyzed α,β-dehydrogenation of carbonyl compounds was developed. A broad spectrum of carbonyls or analogues, such as aldehyde, ketone, lactone, lactam, amine, and alcohol, could be converted to their α,β-unsaturated counterparts in a simple one-step reaction with high yields.

Topics & Concepts

ChemistryDehydrogenationAldehydeKetoneCatalysisAlcoholOrganic chemistryAmine gas treatingCombinatorial chemistryAsymmetric Hydrogenation and CatalysisSynthesis and Catalytic ReactionsAsymmetric Synthesis and Catalysis