Clinical utility of antifungal susceptibility testing
Todd P McCarty, Paul M. Luethy, John W. Baddley, Peter G. Pappas
Abstract
Invasive fungal diseases cause significant morbidity and mortality, in particular affecting immunocompromised patients. Resistant organisms are of increasing importance, yet there are many notable differences in the ability to both perform and interpret antifungal susceptibility testing compared with bacteria. In this review, we will highlight the strengths and limitations of resistance data of pathogenic yeasts and moulds that may be used to guide treatment and predict clinical outcomes.
Topics & Concepts
AntifungalIntensive care medicineAntifungal drugsMedicineBiologyMicrobiologyAntifungal resistance and susceptibilityFungal Infections and StudiesPlant Pathogens and Fungal Diseases