Chelidonine selectively inhibits the growth of gefitinib-resistant non-small cell lung cancer cells through the EGFR-AMPK pathway
Ya‐Jia Xie, Weina Gao, Qibiao Wu, Xiaojun Yao, Zebo Jiang, Yuwei Wang, Wenjun Wang, Wěi Li, Shahid Hussain, Liang Liu, Elaine Lai‐Han Leung, Xing‐Xing Fan
Topics & Concepts
GefitinibT790MAfatinibAMPKCancer researchApoptosisTyrosine kinaseBiologyMitochondrial respiratory chainKinasePharmacologyChemistryMitochondrionEpidermal growth factor receptorSignal transductionCell biologyProtein kinase ABiochemistryReceptorQuinazolinone synthesis and applicationsCancer therapeutics and mechanismsBerberine and alkaloids research