Rapid and sensitive detection of dual lung cancer-associated miRNA biomarkers by a novel SERS-LFA strip coupling with catalytic hairpin assembly signal amplification
Xiaowei Cao, Yue Sun, Yu Mao, Menglin Ran, Yifan Liu, Dan Lü, Caili Bi
Abstract
A novel surface-enhanced Raman scattering-lateral flow assay strip in combination with catalytic hairpin assembly signal amplification has been developed for rapid and sensitive detection of miR-196a-5p and miR-31-5p associated with lung cancer.
Topics & Concepts
Raman scatteringMaterials scienceSIGNAL (programming language)Coupling (piping)Detection limitmicroRNALung cancerCatalysisRaman spectroscopyBiologyOpticsChemistryBiochemistryComputer sciencePathologyChromatographyPhysicsGeneMedicineMetallurgyProgramming languageAdvanced biosensing and bioanalysis techniquesMicroRNA in disease regulationExtracellular vesicles in disease