Metformin: decelerates biomarkers of aging clocks
Ram Abou Zaki, Assam El‐Osta
Abstract
A recent study published in Cell shows the widely known and used antidiabetic drug metformin, has geroprotective benefits in non-human male primates. 1 Metformin is a derivative of biguanide, synthesized in the 1920s and quickly became the first line off-label treatment for type 2 diabetes due to its efficacy in lowering plasma glucose levels.
Topics & Concepts
Molecular biomarkersComputational biologyMetforminMedicineBioinformaticsInternal medicineBiologyEndocrinologyDiabetes mellitusMetabolism, Diabetes, and CancerCircadian rhythm and melatoninCancer-related cognitive impairment studies