Direct observation of prion-like propagation of protein misfolding templated by pathogenic mutants
Krishna Neupane, Abhishek Narayan, Supratik Sen Mojumdar, Gaurav Adhikari, Craig R. Garen, Michael T. Woodside
Topics & Concepts
MutantPrion proteinProtein foldingCell biologyChemistryComputational biologyBiologyBiochemistryGeneMedicinePathologyDiseasePrion Diseases and Protein MisfoldingAmino Acid Enzymes and MetabolismRNA regulation and disease