Structure reveals why genome folding is necessary for site-specific integration of foreign DNA into CRISPR arrays
Andrew Santiago‐Frangos, William S. Henriques, Tanner Wiegand, Colin C. Gauvin, Murat Buyukyoruk, Ava B. Graham, Royce A. Wilkinson, Lenny Triem, Kasahun Neselu, Edward T. Eng, Gabriel C. Lander, Blake Wiedenheft
Topics & Concepts
IntegraseCRISPRDNABiologyPlasmidBase pairGeneticsIntegrasesGenomeComputational biologyGeneCRISPR and Genetic EngineeringRNA and protein synthesis mechanismsBacteriophages and microbial interactions